Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine.

@article{Oroval2016SurfaceER,
  title={Surface Enhanced Raman Scattering and Gated Materials for Sensing Applications: The Ultrasensitive Detection of Mycoplasma and Cocaine.},
  author={Mar Oroval and Marc Coronado-Puchau and Judith A. Langer and Marta Norah Sanz-Ortiz and {\`A}ngela Ribes and Elena Aznar and Carmen Coll and M Dolores Marcos and F{\'e}lix Sancen{\'o}n and Luis M. Liz-Marz{\'a}n and Ram{\'o}n Mart{\'i}nez-M{\'a}{\~n}ez},
  journal={Chemistry},
  year={2016},
  volume={22 38},
  pages={
          13488-95
        }
}
We present herein a novel combination of gated mesoporous silica nanoparticles (MSNs) and surface-enhanced Raman scattering (SERS) for sensing applications. As a proof-of-concept, we show the design of a system comprising MSNs loaded with crystal violet (CV), a molecule with high Raman cross section acting as SERS reporter, and capped with either a suitable DNA sequence for the detection of Mycoplasma genomic DNA or with an aptamer that selectively coordinates cocaine. In both cases the… CONTINUE READING

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