Surface-Displayed IL-10 by Recombinant Lactobacillus plantarum Reduces Th1 Responses of RAW264.7 Cells Stimulated with Poly(I:C) or LPS.

@article{Cai2016SurfaceDisplayedIB,
  title={Surface-Displayed IL-10 by Recombinant Lactobacillus plantarum Reduces Th1 Responses of RAW264.7 Cells Stimulated with Poly(I:C) or LPS.},
  author={Ruopeng Cai and Yanlong Jiang and Wei Yang and Wentao Yang and Shaohua Shi and Chunwei Shi and Jingtao Hu and Wei Gu and Liping Ye and Fangyu Zhou and Qinglong Gong and Wenyu Han and Gui-lian Yang and Chenggang Wang},
  journal={Journal of microbiology and biotechnology},
  year={2016},
  volume={26 2},
  pages={421-31}
}
Recently, poly-γ-glutamic acid synthetase A (pgsA) has been applied to display exogenous proteins on the surface of Lactobacillus casei or Lactococcus lactis, which results in a surfacedisplayed component of bacteria. However, the ability of carrying genes encoded by plasmids and the expression efficiency of recombinant bacteria can be somewhat affected by the longer gene length of pgsA (1,143 bp); therefore, a truncated gene, pgsA, was generated based on the characteristics of pgsA by… CONTINUE READING

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