Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm.

@article{Hu2017SurfaceAdaptiveGN,
  title={Surface-Adaptive Gold Nanoparticles with Effective Adherence and Enhanced Photothermal Ablation of Methicillin-Resistant Staphylococcus aureus Biofilm.},
  author={Dengfeng Hu and Huan Li and Bailiang Wang and Zi Ye and Wenxi Lei and Fan Jia and Qiao Jin and Kefeng Ren and Jian Ji},
  journal={ACS nano},
  year={2017},
  volume={11 9},
  pages={
          9330-9339
        }
}
Biofilms that contribute to the persistent bacterial infections pose serious threats to global public health, mainly due to their resistance to antibiotics penetration and escaping innate immune attacks by phagocytes. Here, we report a kind of surface-adaptive gold nanoparticles (AuNPs) exhibiting (1) a self-adaptive target to the acidic microenvironment of biofilm, (2) an enhanced photothermal ablation of methicillin-resistant Staphylococcus aureus (MRSA) biofilm under near-infrared (NIR… CONTINUE READING

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