Supranodose vagotomy eliminates respiratory depression evoked by dermorphin in anaesthetized rats.


The respiratory effects of stimulation of mu-opioid receptors were studied in spontaneously breathing anaesthetized rats that were either neurally intact or subjected to bilateral supranodosal vagotomy. An intravenous dermorphin bolus of 0.5 mg/kg evoked the apnea followed by breathing of reduced rate and compensatory augmentation of tidal volume, which… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.