Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery.

@article{Liu2007SupramolecularCO,
  title={Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery.},
  author={Zhuang Liu and Xiaoming Sun and Nozomi Nakayama-Ratchford and Hongjie Dai},
  journal={ACS nano},
  year={2007},
  volume={1 1},
  pages={50-6}
}
We show that large surface areas exist for supramolecular chemistry on single-walled carbon nanotubes (SWNTs) prefunctionalized noncovalently or covalently by common surfactant or acid-oxidation routes. Water-soluble SWNTs with poly(ethylene glycol) (PEG) functionalization via these routes allow for surprisingly high degrees of pi-stacking of aromatic molecules, including a cancer drug (doxorubicin) with ultrahigh loading capacity, a widely used fluorescence molecule (fluorescein), and… CONTINUE READING
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