Supramolecular chemical shift reagents inducing conformational transitions: NMR analysis of carbohydrate homooligomer mixtures.

Abstract

We introduce the concept of supramolecular chemical shift reagents as a tool to improve signal resolution for the NMR analysis of homooligomers. Non-covalent interactions with the shift reagent can constrain otherwise flexible analytes inducing a conformational transition that results in signal separation. Here we use this approach for the quantitative analysis of a complex homooligomeric glycan mixture.

DOI: 10.1039/c4cc09710f

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Cite this paper

@article{Beeren2015SupramolecularCS, title={Supramolecular chemical shift reagents inducing conformational transitions: NMR analysis of carbohydrate homooligomer mixtures.}, author={Sophie R Beeren and Sebastian Meier}, journal={Chemical communications}, year={2015}, volume={51 15}, pages={3073-6} }