Supramolecular Fluorescent Nanoparticles Constructed via Multiple Non-Covalent Interactions for the Detection of Hydrogen Peroxide in Cancer Cells.

@article{Wei2015SupramolecularFN,
  title={Supramolecular Fluorescent Nanoparticles Constructed via Multiple Non-Covalent Interactions for the Detection of Hydrogen Peroxide in Cancer Cells.},
  author={Xuan Wei and Ruijiao Dong and Dali Wang Yano Ren Zhong Wang and Tianyu Zhao and Yongsheng Gao and Patrick Duffy and Xinyuan Zhu and Wenxin Wang},
  journal={Chemistry},
  year={2015},
  volume={21 32},
  pages={11427-34}
}
Overabundance of hydrogen peroxide originating from environmental stress and/or genetic mutation can lead to pathological conditions. Thus, the highly sensitive detection of H2 O2 is important. Herein, supramolecular fluorescent nanoparticles self-assembled from fluorescein isothiocyanate modified β-cyclodextrin (FITC-β-CD)/rhodamine B modified ferrocene (Fc-RB) amphiphile were prepared through host-guest interaction between FITC-β-CD host and Fc-RB guest for H2 O2 detection in cancer cells… CONTINUE READING