Supralinear Ca 2 1 Signaling by Cooperative and Mobile Ca 2 1 Buffering in Purkinje Neurons

  title={Supralinear Ca 2 1 Signaling by Cooperative and Mobile Ca 2 1 Buffering in Purkinje Neurons},
  author={Hitoshi Maeda and Graham C. R. Ellis-Davies and Koichi Ito and Yasushi Miyashita and Haruo Kasai},
that mice deficient in calbindin-D 28K exhibit cerebellar ataxia (Airaksinen et al., 1997a) and impaired spatial Hongo, Bunkyo-ku Tokyo 113 learning (Molinari et al., 1996). However, the properties of high-affinity Ca 2ϩ buffering in vivo and its specific Japan † Department of Pharmacology and Physiology consequences for neuronal Ca 2ϩ signaling have not been elucidated. We have therefore now investigated Ca 2ϩ buffering in Purkinje cells with the use of a low-affinity (‫01ف‬ ␮M) Ca 2… CONTINUE READING
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Synthesis of photosensitive EGTA deriv - of D H , whereas those induced by the local input are markedly re - atives

  • G. C. R. Ellis-Davies
  • Tetrahedron Lett .
  • 1998
Highly Influential
13 Excerpts

Research for the Future program of the Japan Society for the Promotion

  • L. Fierro, R. DiPolo, I. Llano
  • J. Physiol
  • 1998
Highly Influential
5 Excerpts

BTC concentration of 0.6 mM, with KBTC 5 15 mM, DBTC 5 100 mm2/s, DCa 5 233 mm2/s, P 5 5/s, and Cr 5 0.1 mM

  • J. Eilers, G. J. Augustine, A. Konnerth
  • Nature
  • 1995
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3 Excerpts

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