Suppressors of Cytokine Signaling in Sickness and in Health of Pancreatic β-Cells


Suppressors of cytokine signaling (SOCS) are a family of eight proteins that negatively regulate Janus kinase and signal transducers and activators of transcription signaling in cells that utilize this pathway to respond to extracellular stimuli. SOCS are best known for attenuating cytokine signaling in the immune system. However, they are also expressed in… (More)
DOI: 10.3389/fimmu.2016.00169