Suppressor T cell memory. Induction and recall of HGG-specific memory suppressor T cells and their role in regulation of antibody production.

Abstract

Regulation of the antibody response to the hapten, dinitrophenyl (DNP), was studied using human gammaglobulin (HGG) as the carrier in an adoptive transfer system. CBA mice immunized at least 4 weeks previously to HGG or DNP served as the source of T helper cells and hapten-primed B cells, respectively. The addition of spleen cells from donors recently… (More)

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