Suppressive effect of cholecystokinin and its related peptides on beta-endorphin-induced catalepsy in rats.

Abstract

The effects of the C-terminal octapeptide of cholecystokinin (CCK-8) and its related peptides on the onset and duration of beta-endorphin-induced catalepsy on injection of the peptides into the lateral ventricle were investigated in male rats. The onset of catalepsy was delayed to some extent by nonsulfated CCK-8 and CCK-7 but CCK-8 and caerulein were ineffective. Naltrexone and caerulein significantly shortened the duration of catalepsy, but CCKs were less effective to shorten it. Pentagastrin had no effect on either parameter.

Statistics

0100020003000'86'89'92'95'98'01'04'07'10'13'16
Citations per Year

326 Citations

Semantic Scholar estimates that this publication has 326 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Itoh1981SuppressiveEO, title={Suppressive effect of cholecystokinin and its related peptides on beta-endorphin-induced catalepsy in rats.}, author={Susumu Itoh and Goro Katsuura}, journal={European journal of pharmacology}, year={1981}, volume={74 4}, pages={381-4} }