Suppressive effect of Ixodes ricinus salivary gland extract on mechanisms of natural immunity in vitro.

@article{Kopeck1998SuppressiveEO,
  title={Suppressive effect of Ixodes ricinus salivary gland extract on mechanisms of natural immunity in vitro.},
  author={J{\'a}n Kopeck{\'y} and M Kuthejlov{\'a}},
  journal={Parasite immunology},
  year={1998},
  volume={20 4},
  pages={169-74}
}
Tick saliva has been shown to contain a variety of pharmacologically active molecules, including those with immunosuppressive activities. There is increasing evidence that the nonspecific suppression of host immunity by tick saliva is exploited by tick-borne pathogens, e.g. the saliva-activated transmission (SAT) of some tick-borne viruses. We have demonstrated the suppressive effect of the salivary gland extract (SGE) derived from partially fed (five days) Ixodes ricinus females on important… CONTINUE READING