Suppression of ventricular arrhythmias by volatile anesthetics in a canine model of chronic myocardial infarction.

@article{Deutsch1990SuppressionOV,
  title={Suppression of ventricular arrhythmias by volatile anesthetics in a canine model of chronic myocardial infarction.},
  author={N. Deutsch and C. Hantler and A. Tait and A. Uprichard and M. Schork and P. Knight},
  journal={Anesthesiology},
  year={1990},
  volume={72 6},
  pages={
          1012-21
        }
}
Ventricular tachycardia likely secondary to a reentrant mechanism may be reliably induced by programmed electrical stimulation in dogs 4-6 days after creating a 2-h experimental, occlusion-reperfusion myocardial infarction. The effects of 1.1 and 1.8 MAC halothane, isoflurane, and enflurane on pacing-induced arrhythmias were studied in this model. The ease of initiation of ventricular tachycardia was measured in both awake and anesthetized dogs (n = 18). Excitation thresholds, conduction times… Expand
Electrophysiologic effects of volatile anesthetics, sevoflurane and halothane, in a canine myocardial infarction model
TLDR
It is concluded that sevoflurane as well as halothane selectively depresed the delayed activation and the prolongation of ERP in myocardial infarction, which may inhibit ventricular arrhythmias in my Cardiac Infarction. Expand
Effects of volatile anesthetics, enflurane, isoflurane, and halothane on ventricular delayed activation in a canine myocardial infarction model.
TLDR
Enflurane and halothane produced marked depression of delayed activation in myocardial infarction, which may affect, that is, inhibit or provoke, ventricular arrhythmias in my Cardiac Infarction. Expand
Electrophysiologic interaction between class I antiarrhythmic drugs and volatile anesthetics in depressant effects on ventricular activation in a canine myocardial infarction model.
TLDR
The electrophysiologic interaction between volatile anesthetics and class I antiarrhythmic drugs (lidocaine, procainamide) in effects on the ventricular delayed activation in a canine myocardial infarction model was examined and a synergistic interaction was observed. Expand
Comparison of the effects of halothane and propranolol on the effective refractory period and the ventricular activation in a canine myocardial infarction model.
TLDR
Halothane produced a selective depression of the delayed activation and the prolongation of ERP, which may be caused by both direct effects on the myocardium and secondary effects such as a reduction of the heart rate. Expand
Actions of halothane and isoflurane on Purkinje fibers in the infarcted canine heart: conduction, regional refractoriness, and reentry.
TLDR
The actions of halothane and isoflurane were studied in infarcted canine hearts to compare their effects on reentry in vitro and an extrastimulus technique was used to determine the relationship between delay of conduction of premature impulses into the more refractory ischemic region and induction of reentrant responses. Expand
Does Anesthesia Induction during Electrophysiologic Studies Induce Tachycardia in Pediatric Patients
TLDR
Sinus Tachycardia occurred in 10% of pediatric electrophysiology cases performed under general anesthesia, and was seen more frequently when IH agents were used compared to IV. Expand
New aspects of cardiac electrophysiology and function: effects of inhalational anaesthetics
TLDR
Although volatile anaesthetics produce decreases in contractility and alterations in diastolic function, some of these agents also have important protective effects on postischaemic, reperfused (stunned) myocardium. Expand
Placement of an automatic implantable cardioverter-defibrillator in a 6-month-old infant: anesthetic management.
TLDR
A case of AICD insertion under caudal epidural and general anesthesia in a 6-month-old infant suffering from ventricular tachyarrhythmia as a result of a large right ventricnlar congenital tumor is reported. Expand
Methoxyflurane anesthesia augments the chronotropic and dromotropic effects of verapamil.
  • F. Jamali, P. Mayo
  • Medicine
  • Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
  • 1999
TLDR
General anesthesia with MF enhances the dromotropic and chronotropic effect of verapamil in the rat and should be considered when MF-anesthesia is used in experimental procedure. Expand
Electrophysiological mechanisms for ventricular arrhythmias in patients with myocardial ischemia: anesthesiologic considerations, Part 1.
  • J. Gallagher
  • Medicine
  • Journal of cardiothoracic and vascular anesthesia
  • 1997
Abstract This is the second half of a two-part review article that discusses ventricular tachyarrhythmias, either induced by acute ischemia or consequent to chronic myocardial ischemia, and theirExpand
...
1
2
3
...