Suppression of tumour necrosis factor-alpha by Schizonepeta tenuifolia water extract via inhibition of IkappaBalpha degradation and Jun N-terminal kinase/stress-activated protein kinase activation.

Abstract

OBJECTIVES The anti-inflammatory effects of an aqueous extract of Schizonepeta tenuifolia on lipopolysaccharide (LPS)-induced tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) in vivo and in vitro have been investigated. METHODS C57BL/6 mice were orally administered phosphate-buffered saline (control) or S. tenuifolia water extract (50… (More)
DOI: 10.1111/j.2042-7158.2010.01126.x

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