Suppression of tumor growth by intra-muscular transfer of naked DNA encoding adrenomedullin antagonist


We have recently reported that the intra-tumoral injection of adrenomedullin (AM) antagonist (AMA; AM (22–52)) peptides significantly reduced the in vivo growth of a pancreatic cancer cell line in severely combined immunodeficient (SCID) mice. In the present study, we examined the effects of intra-tumoral and intra-muscular transfers of naked DNA encoding… (More)
DOI: 10.1038/sj.cgt.7700979


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