Suppression of the Nuclear Factor‐κB Activation Pathway by Spice‐Derived Phytochemicals: Reasoning for Seasoning

@article{Aggarwal2004SuppressionOT,
  title={Suppression of the Nuclear Factor‐κB Activation Pathway by Spice‐Derived Phytochemicals: Reasoning for Seasoning},
  author={B. Aggarwal and S. Shishodia},
  journal={Annals of the New York Academy of Sciences},
  year={2004},
  volume={1030}
}
Abstract: The activation of nuclear transcription factor κB has now been linked with a variety of inflammatory diseases, including cancer, atherosclerosis, myocardial infarction, diabetes, allergy, asthma, arthritis, Crohn's disease, multiple sclerosis, Alzheimer's disease, osteoporosis, psoriasis, septic shock, and AIDS. Extensive research in the last few years has shown that the pathway that activates this transcription factor can be interrupted by phytochemicals derived from spices such as… Expand
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References

SHOWING 1-10 OF 77 REFERENCES
Nuclear factor-κB: its role in health and disease
  • 772
Activation of Transcription Factor NF-κB Is Suppressed by Curcumin (Diferuloylmethane) (*)
  • 1,132
  • PDF
A novel mechanism for the inhibition of NFκB activation in vascular endothelial cells by natural antioxidants
  • S. Schubert, I. Neeman, N. Resnick
  • Biology, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2002
  • 127
Anticancer potential of curcumin: preclinical and clinical studies.
  • 2,280
  • PDF
...
1
2
3
4
5
...