Suppression of the Inflammatory Cascade is Implicated in Resveratrol Chemoprevention of Experimental Hepatocarcinogenesis

@article{Bishayee2010SuppressionOT,
  title={Suppression of the Inflammatory Cascade is Implicated in Resveratrol Chemoprevention of Experimental Hepatocarcinogenesis},
  author={Anupam Bishayee and Abhijeet Waghray and Kendra F. Barnes and Thomas S Mbimba and Deepak Bhatia and Malay Chatterjee and Altaf S. Darvesh},
  journal={Pharmaceutical Research},
  year={2010},
  volume={27},
  pages={1080-1091}
}
ABSTRACTPurposeResveratrol, present in grapes and red wine, has been found to prevent diethylnitrosamine (DENA)-initiated rat liver tumorigenesis, though the chemopreventive mechanisms are not completely elucidated. The current study was designed to explore whether the antiinflammatory properties of resveratrol play a role in its antihepatocarcinogenic action.MethodsLiver samples were harvested from a 20-week chemopreventive study in which resveratrol (50, 100 and 300 mg/kg) was shown to… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 42 CITATIONS

Resveratrol and liver: A systematic review

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  • 2015
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The pharmacology of resveratrol in animals and humans.

  • Biochimica et biophysica acta
  • 2015
VIEW 16 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Resveratrol and cancer: focus on in vivo evidence

VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 73 REFERENCES

Expressions of HSP70 and HSP27 in Hepatocellular Carcinoma

  • Journal of Korean medical science
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Chemopreventive doses of resveratrol do not affect cardiac function in a rodent model of hepatocellular carcinoma

DJ Luther, V Ohanyan, +3 authors TD Booth
  • Invest New Drugs
  • 2010
VIEW 1 EXCERPT