Suppression of postoperative systemic inflammatory response syndrome with clarithromycin following lung cancer surgery.

@article{Hirata2004SuppressionOP,
  title={Suppression of postoperative systemic inflammatory response syndrome with clarithromycin following lung cancer surgery.},
  author={Toshiki Hirata and Eiji Ogawa and Katsu Takenaka and F Kawashita},
  journal={European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes},
  year={2004},
  volume={36 1},
  pages={13-9}
}
We examined whether clarithromycin (CAM), a 14-membered macrolide, can control the postoperative systemic inflammatory response syndrome that occurs following lung cancer surgery. In the control group (n = 16), prophylactic antibiotics (flomoxef) were administered for 4-7 days following surgery. In the CAM group (n = 10), 400 mg/day of CAM were administered orally for 14 days prior to surgery and for 7 days following surgery, in addition to the postoperative administration of flomoxef. The… CONTINUE READING