Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor ( PPAR ) and and PPAR coactivator 1 in human skeletal muscle , but not lipid regulatory genes

@inproceedings{Watt2004SuppressionOP,
  title={Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor ( PPAR ) and and PPAR coactivator 1 in human skeletal muscle , but not lipid regulatory genes},
  author={Matthew J Watt and Robert J. Southgate and Anna Greer Holmes and Mark Anthony Febbraio},
  year={2004}
}
Fatty acids are an important ligand for peroxisome proliferator-activated receptor (PPAR) activation and transcriptional regulation of metabolic genes. To examine whether reduced plasma free fatty acid (FFA) availability affects the mRNA content of proteins involved in fuel metabolism in vivo, the skeletal muscle mRNA content of various transcription factors, transcriptional coactivators and genes encoding for lipid regulatory proteins were examined before and after 3 h of cycle exercise with… CONTINUE READING

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