Suppression of mitogenic response of bovine peripheral blood lymphocytes by ketone bodies.

@article{Sato1995SuppressionOM,
  title={Suppression of mitogenic response of bovine peripheral blood lymphocytes by ketone bodies.},
  author={Shizuo Sato and Tatsuo Suzuki and Keiji Okada},
  journal={The Journal of veterinary medical science},
  year={1995},
  volume={57 1},
  pages={183-5}
}
Mitogenic response of peripheral blood lymphocytes from ketotic cows and effect of ketone bodies on lymphocyte blastogenesis were investigated. Glucose consumption index (GCI) values for phytohaemagglutinin (PHA), concanavalin A (Con A) and pokeweed mitogen (PWM) in the ketotic cows were significantly lower than those in the healthy dry cows. A significant negative correlation was observed between the GCI values and serum concentrations of total ketone and beta-hydroxybutyric acid. When… CONTINUE READING

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