Suppression of meal size by intestinal nutrients is eliminated by celiac vagal deafferentation.

@article{Walls1995SuppressionOM,
  title={Suppression of meal size by intestinal nutrients is eliminated by celiac vagal deafferentation.},
  author={Elwood K. Walls and Robert J. Phillips and Feng Wang and Mike Holst and T L Powley},
  journal={The American journal of physiology},
  year={1995},
  volume={269 6 Pt 2},
  pages={R1410-9}
}
The arrival of nutrients in the gastrointestinal tract suppresses intake. To specify the neural pathways and receptor locations of this feedback, we examined the effects of intraduodenal infusions of 10 nutrients plus saline on short-term food intake of rats with selective deafferentations of vagal celiac branches. Three response profiles were observed: 1) isotonic saline, 5.6% glycerol, and 3% fructose did not inhibit intake of controls or selectively deafferented animals; 2) 3% glucose, 3… CONTINUE READING