Suppression of matrix metalloproteinase production from synovial fibroblasts by meloxicam in-vitro.

Abstract

The aim of this study was to evaluate the influence of meloxicam on the production of both matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) from human synovial fibroblasts by TNF-alpha stimulation in-vitro. Synovial fibroblasts (2 x 10(4) cells/mL) derived from patients with osteoarthritis were stimulated with 20.0 ng mL… (More)

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@article{Asano2006SuppressionOM, title={Suppression of matrix metalloproteinase production from synovial fibroblasts by meloxicam in-vitro.}, author={Kazuhito Asano and Misako Sakai and Takako Matsuda and Hironori Tanaka and Keigo Fujii and Tadashi Hisamitsu}, journal={The Journal of pharmacy and pharmacology}, year={2006}, volume={58 3}, pages={359-66} }