Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists.

@article{Szab1998SuppressionOM,
  title={Suppression of macrophage inflammatory protein (MIP)-1alpha production and collagen-induced arthritis by adenosine receptor agonists.},
  author={Csaba Szab{\'o} and Gwen S. Scott and L{\'a}szl{\'o} Vir{\'a}g and Gregory F. Egnaczyk and Andrew L. Salzman and Thomas P. Shanley and Gy{\"o}rgy Hask{\'o}},
  journal={British journal of pharmacology},
  year={1998},
  volume={125 2},
  pages={
          379-87
        }
}
1. Ligands of the various adenosine receptor subtypes modulate the production of pro-and anti-inflammatory cytokines. Here we evaluated the effect of adenosine and various ligands of the adenosine receptor subtypes (A1, A2, A3) on the chemokine macrophage inflammatory protein (MIP) 1alpha production in immunostimulated RAW macrophages in vitro. Furthermore, we studied whether a selected A3 adenosine receptor agonist inhibits MIP-1alpha production and affects the course of inflammation in… CONTINUE READING

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