Suppression of lung metastases by the CD26/DPP4 inhibitor Vildagliptin in mice

Abstract

Metastases rather than primary cancers determine nowadays the survival of patients. One of the most common primary malignancies is colorectal cancer and this type of tumor is characterized by a high tendency to spread metastases to the lung and liver. CD26/DPP4 is a transmembrane molecule with enzymatic functions which cleaves biologically active peptides… (More)
DOI: 10.1007/s10585-015-9736-z

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