Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor.

@article{Larsson2002SuppressionOI,
  title={Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor.},
  author={Elin Larsson and Ronald J. Mandel and Ronald L. Klein and Nicholas Muzyczka and Olle Lindvall and Zaal Kokaia},
  journal={Experimental neurology},
  year={2002},
  volume={177 1},
  pages={1-8}
}
In mammals, including humans, the subventricular zone of the lateral ventricle and the subgranular zone of the dentate gyrus contain neural stem cells, which continue to proliferate even in adulthood and give rise to new neurons. Neurogenesis in these areas is enhanced by brain insults. Brain-derived neurotrophic factor (BDNF) promotes neuronal survival and… CONTINUE READING