Suppression of hippocampal epileptic seizures in the kainate rat by Poisson distributed stimulation

@article{Wyckhuys2010SuppressionOH,
  title={Suppression of hippocampal epileptic seizures in the kainate rat by Poisson distributed stimulation},
  author={T. Wyckhuys and P. Boon and R. Raedt and B. Van Nieuwenhuyse and K. Vonck and W. Wadman},
  journal={Epilepsia},
  year={2010},
  volume={51}
}
Purpose:  Hippocampal deep brain stimulation (DBS) is an experimental therapy for patients with pharmacoresistant temporal lobe epilepsy (TLE). Despite the successful clinical application of DBS, the optimal stimulation parameters are undetermined. We evaluate the efficacy of a new form of DBS, using continuous stimuli with Poisson distributed intervals (Poisson distributed stimulation, PDS) in the kainate (KA) rat model, a validated model for human TLE. 
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