Suppression of hepcidin during anemia requires erythropoietic activity.

@article{Pak2006SuppressionOH,
  title={Suppression of hepcidin during anemia requires erythropoietic activity.},
  author={Mihwa Pak and Miguel A. L{\'o}pez and Victroia Gabayan and Tomas Ganz and Seth Rivera},
  journal={Blood},
  year={2006},
  volume={108 12},
  pages={
          3730-5
        }
}
Hepcidin, the principal iron regulatory hormone, regulates the absorption of iron from the diet and the mobilization of iron from stores. Previous studies indicated that hepcidin is suppressed during anemia, a response that would appropriately increase the absorption of iron and its release from stores. Indeed, in the mouse model, hepcidin-1 was suppressed after phlebotomy or erythropoietin administration but the suppression was reversed by inhibitors of erythropoiesis. The suppression of… CONTINUE READING

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