Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats.

@article{Kannappan2010SuppressionOH,
  title={Suppression of hepatic oxidative events and regulation of eNOS expression in the liver by naringenin in fructose-administered rats.},
  author={Sriramajayam Kannappan and Nallasamy Palanisamy and Carani Venkataraman Anuradha},
  journal={European journal of pharmacology},
  year={2010},
  volume={645 1-3},
  pages={177-84}
}
Previous studies show that naringenin promotes insulin sensitivity in fructose-fed rats. This study investigates whether naringenin prevents oxidative events and apoptotic changes triggered in the rat liver by a high fructose diet. Male Wistar rats of body weight 150-180 g were fed either diet containing starch (60% carbohydrate) or fructose (60% fructose diet). From the 16th day of feeding, rats in each dietary group were divided into two, and treated or not with naringenin (50mg/kg b.w/day… CONTINUE READING