Suppression of cell-mediated immunity in experimental African trypanosomiasis.

  title={Suppression of cell-mediated immunity in experimental African trypanosomiasis.},
  author={John M. Mansfield and J H Wallace},
  journal={Infection and immunity},
  volume={10 2},
Adult New Zealand white rabbits were experimentally infected with a parasitic African hemoflagellate, Trypanosoma congolense, and were subsequently tested for in vivo and in vitro aspects of cell-mediated immune function. Chronically infected rabbits were sensitized to mycobacterial protein and skin-tested with purified protein derivative; all infected animals demonstrated much milder skin-test responses to antigen than control groups. Similarly, peripheral blood lymphocyte responses in vitro… CONTINUE READING
Highly Cited
This paper has 344 citations. REVIEW CITATIONS


Publications citing this paper.

345 Citations

Citations per Year
Semantic Scholar estimates that this publication has 345 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…