Suppression of c-myc and c-myb is tightly linked to terminal differentiation induced by IL6 or LIF and not growth inhibition in myeloid leukemia cells.

@article{HoffmanLiebermann1991SuppressionOC,
  title={Suppression of c-myc and c-myb is tightly linked to terminal differentiation induced by IL6 or LIF and not growth inhibition in myeloid leukemia cells.},
  author={Barbara Hoffman-Liebermann and Dan A. Liebermann},
  journal={Oncogene},
  year={1991},
  volume={6 6},
  pages={903-9}
}
Cell proliferation and differentiation are intimately related processes where the proto-oncogenes c-myc and c-myb have been implicated to play a role. Previously, we have shown that both c-myc and c-myb were induced in normal myeloid precursors when the cells were stimulated for growth, were expressed in the autonomously proliferating myeloid leukemic M1… CONTINUE READING