Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47

@article{Saini2016SuppressionOA,
  title={Suppression of autophagy and antigen presentation by Mycobacterium tuberculosis PE_PGRS47},
  author={Neeraj Saini and Andr{\'e}s Baena and Tony Chon Wee Ng and Manjunatha Muniswamappa Venkataswamy and Steven C. Kennedy and Shajo Kunnath-Velayudhan and Leandro J Carre{\~n}o and Jiayong Xu and John Chan and Michelle H. Larsen and William Robert Jacobs and Steven A. Porcelli},
  journal={Nature Microbiology},
  year={2016},
  volume={1}
}
Suppression of major histocompatibility complex (MHC) class II antigen presentation is believed to be among the major mechanisms used by Mycobacterium tuberculosis to escape protective host immune responses. Through a genome-wide screen for the genetic loci of M. tuberculosis that inhibit MHC class II-restricted antigen presentation by mycobacteria-infected… CONTINUE READING