Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases.

Abstract

In many cell types, position in the cell cycle appears to play a role in determining susceptibility to apoptosis (programmed cell death), and expression of various cyclins and activation of cyclin-dependent kinases (CDKs) have been shown to correlate with the onset of apoptosis in a number of experimental systems. To assess the role of CDK-mediated cell… (More)

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@article{Meikrantz1996SuppressionOA, title={Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases.}, author={W Meikrantz and Robert A. Schlegel}, journal={The Journal of biological chemistry}, year={1996}, volume={271 17}, pages={10205-9} }