Suppression of allergic response by CpG motif oligodeoxynucleotide-house-dust mite conjugate in animal model of allergic rhinitis.

@article{Mo2006SuppressionOA,
  title={Suppression of allergic response by CpG motif oligodeoxynucleotide-house-dust mite conjugate in animal model of allergic rhinitis.},
  author={Ji-Hun Mo and Seok-won Park and Chae-Seo Rhee and Kenji Takabayashi and Seung Sin Lee and Song-Hua Quan and In-Sang Kim and Il Yang-Gi Min and Eyal Raz and Chul Hee Lee},
  journal={American journal of rhinology},
  year={2006},
  volume={20 2},
  pages={212-8}
}
BACKGROUND Although there have been many therapeutic options for allergic disease, the true allergen desensitization remains a challenging goal. The classic immunotherapy has a limited efficacy, is inconvenient, and has a risk of anaphylaxis. Recent reports revealed that immunostimulatory DNA sequences (ISS-oligdeoxynucleotide [ODN], CpG motif) act as a… CONTINUE READING