Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora.

@article{Okabe2014SuppressionOA,
  title={Suppression of adipocyte hypertrophy by polymethoxyflavonoids isolated from Kaempferia parviflora.},
  author={Y. Okabe and T. Shimada and Takumi Horikawa and K. Kinoshita and K. Koyama and K. Ichinose and M. Aburada and K. Takahashi},
  journal={Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year={2014},
  volume={21 6},
  pages={
          800-6
        }
}
  • Y. Okabe, T. Shimada, +5 authors K. Takahashi
  • Published 2014
  • Biology, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • We previously demonstrated that ethyl acetate extracts of Kaempferia parviflora Wall. Ex Baker (KPE) improve insulin resistance in TSOD mice and showed that its components induce differentiation and adipogenesis in 3T3-L1 preadipocytes. The present study was undertaken to examine whether KPE and its isolated twelve components suppress further lipid accumulation in 3T3-L1 mature adipocytes. KPE reduced intracellular triglycerides in mature adipocytes, as did two of its components, 3,5,7,3',4… CONTINUE READING
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