Suppression of actively induced experimental autoimmune uveoretinitis by CD4+ T cells

@article{Uchio1997SuppressionOA,
  title={Suppression of actively induced experimental autoimmune uveoretinitis by CD4+ T cells},
  author={Eiichi Uchio and Masaya Kijima and Misaki Ishioka and Shun-ichi Tanaka and Shigeaki Ohno},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={1997},
  volume={235},
  pages={97-102}
}
• Background: Helper/inducer T cells that exert an inhibitory effect on disease induction have been recently found in many experimental models. In order to clarify the mechanisms of spontaneous remission of experimental autoimmune uveoretinitis (EAU), we investigated the inhibitory effect and the phenotype of the post-recovery suppressor cells. • Methods: In a series of experiments, we separated spleen cells of rats that had recovered from EAU. Three groups of spleen cells, CD4+ T, CD8+ T and B… CONTINUE READING