Suppression of active cross-bridge motions of isolated thick myofilaments in suspension by phenylmethylsulfonyl fluoride.

@article{Fan1985SuppressionOA,
  title={Suppression of active cross-bridge motions of isolated thick myofilaments in suspension by phenylmethylsulfonyl fluoride.},
  author={S F Fan and Maynard M. Dewey and David E. Colflesh and Bruce Gaylinn and R A Greguski and Benjamin Chu},
  journal={Biochimica et biophysica acta},
  year={1985},
  volume={827 1},
  pages={101-5}
}
Studies of photoelectron count autocorrelation function of light scattered from suspensions of thick filaments of Limulus telson muscle and scallop striated adductor muscle reveal that Ca2+ can activate cross-bridge motions of these isolated filaments. By treating suspensions of activated filaments with phenylmethylsulfonyl fluoride (PMSF), we can suppress active cross-bridge motions but not affect the Ca2+-dependent ATPase activity. 

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