Suppression of TH2-type allergic reactions by helminth infection

  title={Suppression of TH2-type allergic reactions by helminth infection},
  author={Padraic G Fallon and Niamh E. Mangan},
  journal={Nature Reviews Immunology},
There is no immunological mechanism to adequately explain the sudden epidemic in allergies noted in the last 30 years in developed countries. The reduction in the development of allergic disorders observed in individuals infected with parasitic helminths, however, supports a possible role for worms in suppressing allergies. Helminths regulate the immunity of the host to ensure a mutually beneficial environment for the survival of both the parasite and the host. This interplay between helminths… CONTINUE READING
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