Suppression of TGF-beta signaling in both normal conjunctival fibroblasts and pterygial body fibroblasts by amniotic membrane.

@article{Lee2000SuppressionOT,
  title={Suppression of TGF-beta signaling in both normal conjunctival fibroblasts and pterygial body fibroblasts by amniotic membrane.},
  author={Seongmu Lee and De-quan Li and Donald Tiang-Hwee Tan and Daniel Meller and Scheffer C. G. Tseng},
  journal={Current eye research},
  year={2000},
  volume={20 4},
  pages={325-34}
}
PURPOSE When used as an alternative substrate following bare sclera removal of pterygium and other ocular surface diseases, amniotic membrane transplantation can reduce scarring on the reconstructed conjunctival surface. This study was carried out to determine if the amniotic membrane (AM) suppresses the expression of the TGFb signaling system in cultured normal conjunctival (HCF) and pterygial body fibroblasts (PBF). METHODS HCF and PBF were cultured on AM and plastic wells in serum… CONTINUE READING
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