Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa

  title={Suppression of T lymphocyte activity by lupeol isolated from Crataeva religiosa},
  author={Sarang Bani and Anpurna Kaul and Beenish Khan and Sheikh Fayaz Ahmad and Krishan Avtar Suri and B. D. Gupta and N. K. Satti and Gulam Nabi Qazi},
  journal={Phytotherapy Research},
Lupeol has been shown to possess antiarthritic activity through possible suppression of the immune system. As seen in the following studies, it was found to suppress various immune factors such as the phagocytic (cell‐killing) activity of macrophages, T‐lymphocyte activity that included CD4+T cell mediated cytokine generation. Assessment of T cells and their intracellular content of cytokines was carried out by flow cytometric analysis in Balb/c mice. Oral administration of lupeol at doses of… 

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