Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases.

Abstract

BACKGROUND & AIMS Activation of lamina propria T cells with pokeweed mitogen in human fetal gut explant cultures results in severe mucosal injury. In the same system, Staphylococcus aureus enterotoxin B produces villus atrophy and crypt cell hyperplasia. The aim of this study was to examine the ability of interleukin (IL)-10 to modify these changes… (More)

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Cite this paper

@article{Pender1998SuppressionOT, title={Suppression of T cell-mediated injury in human gut by interleukin 10: role of matrix metalloproteinases.}, author={Sue Pender and Emma J. Breese and U. G{\"u}nther and D. Howie and Nadine Wathen and Delphan Schuppan and Thomas MacDonald}, journal={Gastroenterology}, year={1998}, volume={115 3}, pages={573-83} }