Suppression of QRFP 43 in the hypothalamic ventromedial nucleus of Long-Evans rats fed a high-fat diet.

@article{Beck2009SuppressionOQ,
  title={Suppression of QRFP 43 in the hypothalamic ventromedial nucleus of Long-Evans rats fed a high-fat diet.},
  author={Bernard Beck and S{\'e}bastien Richy},
  journal={Biochemical and biophysical research communications},
  year={2009},
  volume={383 1},
  pages={78-82}
}
QRFP 43 is a RFamide peptide present in the ventromedial nucleus (VMN) and lateral hypothalamus. It stimulates food intake in mice and its chronic infusion induces hyperphagia, reduced thermogenesis, and obesity. In this experiment, we measured it in the VMN and lateral hypothalamus of Long-Evans rats fed either a high-fat (HF), control, or low-fat (LF) diet in parallel with plasma leptin, adiposity, and energy intake. After 8weeks of ad libitum diet intake, energy intake of HF rats was similar… CONTINUE READING

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