Suppression of D-galactosamine-induced rat liver injury by glycosidic flavonoids-rich fraction from green tea.

@article{Wada1999SuppressionOD,
  title={Suppression of D-galactosamine-induced rat liver injury by glycosidic flavonoids-rich fraction from green tea.},
  author={Seiki Wada and Pei-min He and Naoharu Watanabe and Kanzo Sakata and Kimio Sugiyama},
  journal={Bioscience, biotechnology, and biochemistry},
  year={1999},
  volume={63 3},
  pages={570-2}
}
Tea constituents that had a preventive effect on D-galactosamine-induced liver injury in rats were partially purified by column chromatography from a n-butanol-soluble fraction of green tea. The fraction containing glycosidic flavonoids was found to suppress the D-galactosamine-induced increase of plasma alanine aminotransferase and aspartate aminotransferase activities. These results indicate that glycosidic flavonoids contribute, at least in part, to the liver injury-preventive effect of… CONTINUE READING