Suppression by Hydrangeae Dulcis Folium of D-Galactosamine-induced Liver Injury in Vitro and in Vivo

@article{Nakagiri2003SuppressionBH,
  title={Suppression by Hydrangeae Dulcis Folium of D-Galactosamine-induced Liver Injury in Vitro and in Vivo},
  author={R. Nakagiri and E. Hashizume and S. Kayahashi and Y. Sakai and T. Kamiya},
  journal={Bioscience, Biotechnology, and Biochemistry},
  year={2003},
  volume={67},
  pages={2641 - 2643}
}
  • R. Nakagiri, E. Hashizume, +2 authors T. Kamiya
  • Published 2003
  • Medicine, Biology
  • Bioscience, Biotechnology, and Biochemistry
  • Hydrangeae Dulcis Folium, the fermented and dried leaves of Hydrangea macrophylla SER. var. thunbergii MAKINO, suppressed D-galactosamine-induced liver injury by 85.2% when added to the diet at 1% and fed to rats for fifteen days. The hepatoprotective effect is more potent than that of a milk thistle extract and turmeric powder. Some fractionated extracts showed hepatoprotective activity in the D-galactosamine-induced in vitro liver injury model. 
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