Suppression by 17beta-estradiol of monocyte adhesion to vascular endothelial cells is mediated by estrogen receptors.

@article{Mori2004SuppressionB1,
  title={Suppression by 17beta-estradiol of monocyte adhesion to vascular endothelial cells is mediated by estrogen receptors.},
  author={Michiko Mori and Fujiko Tsukahara and Toshimasa Yoshioka and Kaoru Irie and Hiroaki Ohta},
  journal={Life sciences},
  year={2004},
  volume={75 5},
  pages={
          599-609
        }
}
Several observational studies have shown that estrogen replacement therapy decreases cardiovascular mortality and morbidity in postmenopausal women. However, The Women's Health Initiative (WHI) study has found that women receiving estrogen plus progestin had a significantly higher risk of breast cancer, coronary heart disease, stroke, and pulmonary embolus. In the present study, we examined whether estrogen prevents mechanisms that relate to plaque formation by inhibiting monocyte adhesion to… CONTINUE READING
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