Suppression and recovery of the alveolar macrophage phagocytic system during continuous exposure to 0.5 ppm ozone.

@article{Gilmour1991SuppressionAR,
  title={Suppression and recovery of the alveolar macrophage phagocytic system during continuous exposure to 0.5 ppm ozone.},
  author={M Ian Gilmour and R R Hmieleski and Elizabeth A. Stafford and George J. Jakab},
  journal={Experimental lung research},
  year={1991},
  volume={17 3},
  pages={547-58}
}
Short-term exposures to ozone (O3) are known to impair pulmonary antibacterial defenses and alveolar macrophage (AM) phagocytosis in a dose-related manner. To determine the effect of prolonged O3 exposure, Swiss mice were exposed continuously to 0.5 ppm O3. At 1, 3, 7, and 14 days, intrapulmonary killing was assessed by inhalation challenge with… CONTINUE READING