Suppressing renal NADPH oxidase to treat diabetic nephropathy.

Abstract

Renal nicotinamide adenine dinucleotide phosphate reduced form (NADPH) oxidase is an important source of oxidative stress and its expression is enhanced in the glomerulus and distal tubules of diabetic nephropathy. High glucose-induced protein kinase C signalling or renal angiotensin II signalling increases the membrane translocation of cytosolic component… (More)

Topics

  • Presentations referencing similar topics