Suppressed expression of tubedown-1 in retinal neovascularization of proliferative diabetic retinopathy.

@article{Gendron2001SuppressedEO,
  title={Suppressed expression of tubedown-1 in retinal neovascularization of proliferative diabetic retinopathy.},
  author={Robert L. Gendron and William Vance Good and Lisa C Adams and H{\'e}l{\`e}ne Paradis},
  journal={Investigative ophthalmology & visual science},
  year={2001},
  volume={42 12},
  pages={3000-7}
}
PURPOSE Retinal neovascularization occurring as a complication of diabetes mellitus can cause vision loss and blindness. The identification and study of novel genes involved in retinal angiogenesis may define new targets to suppress retinal neovascularization in diabetes and other ocular diseases. A novel acetyltransferase subunit, tubedown-1 (tbdn-1), has been isolated, the expression of which is regulated during blood vessel development. Tbdn-1 is not detected in most adult vascular beds but… CONTINUE READING