Supporting Material: Synchrony of Cardiomyocyte Ca2+ Release Is Controlled by T-tubule Organization, Sr Ca2+ Content, and Ryanodine Receptor Ca2+ Sensitivity

  • Published 2013


which translates to roughly 12.000 ions per second, i.e. 0.03 pA. This is a factor 100 smaller than the cited current. However, to raise [Ca]i by 0.15 μM (from 0.1 to 0.25) within the same cube, 2μm3×0.15μmol l−1 = 0.3×10−21 mol' 180 ions are needed, i.e. roughly 15.000 ions per second and 0.04 pA. Thus the chosen value for β should give realistic values… (More)