Support for the minimal essential MHC hypothesis: a parrot with a single, highly polymorphic MHC class II B gene

@article{Hughes2008SupportFT,
  title={Support for the minimal essential MHC hypothesis: a parrot with a single, highly polymorphic MHC class II B gene},
  author={Colin R. Hughes and Shana M Miles and Jaclyn M. Walbroehl},
  journal={Immunogenetics},
  year={2008},
  volume={60},
  pages={219-231}
}
We characterized the MHC class II B gene in the green-rumped parrotlet, Forpus passerinus. Three approaches were used: polymerase chain reaction amplification using primers complementary to conserved regions of exon 2, sequencing clones from a genomic library, and amplification of exon 2 using species-specific primers. All three methods indicate that there is only a single class II B locus in this species and no pseudogenes. We suggest that this is the ancestral state for birds. The gene is… CONTINUE READING

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