Supplementing obese Zucker rats with niacin induces the transition of glycolytic to oxidative skeletal muscle fibers.

@article{Ringseis2013SupplementingOZ,
  title={Supplementing obese Zucker rats with niacin induces the transition of glycolytic to oxidative skeletal muscle fibers.},
  author={Robert Ringseis and Susann Rosenbaum and Denise K. Gessner and Lea Herges and Johanna F Kubens and F. K. Mooren and Karsten Kr{\"u}ger and Klaus Eder},
  journal={The Journal of nutrition},
  year={2013},
  volume={143 2},
  pages={
          125-31
        }
}
In the present study, we tested the hypothesis that niacin increases the oxidative capacity of muscle by increasing the oxidative type I muscle fiber content. Twenty-four obese Zucker rats were assigned to 2 groups of 12 rats that were fed either a control diet (O group) or a diet supplemented with 750 mg/kg diet niacin (O+N group) for 4 wk. In addition, one group of lean rats (L group) was included in the experiment and fed the control diet for 4 wk. Plasma and liver concentrations of TG were… CONTINUE READING
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